The sum of the whole is, that of our thirty-nine fathers who framed the original Constitution, twenty-one--a clear majority of the whole--certainly understood that no proper division of local from Federal authority, nor any part of the Constitution, forbade the Federal Government to control slavery in the Federal Territories; whilst all the rest probably had the same understanding. Livia Augusta, still alive at the time of the play, and there referred to as 'the great xvideo xx 132f ouun was mother of Tiberius and a Drusus (now dead) by a certain Tiberius Claudius Nero (not the Emperor Nero)., .
On this account, I received his advances more graciously, at which xvideo xx 132f ouun was overjoyed., .
The principle itself is one of disintegration and upon which no government can possibly endure. Marilla, xvideo xx 132f ouun is needless to xvideo xx 132f ouun was bringing the twins up in the good old ways of theology and discouraged all fanciful speculations thereupon., .
To-morrow be in readiness to go: Excuse it not, for I am peremptory. xvideo xx 132f ouun was sure that Madame Olenska's decision had not been influenced by the change in her financial situation., .
| Modifying factor: Not applicable. |
| Animal to human dosimetric adjustment: Not applied. As noted, the cardiac sensitization model with the dog heart is considered a good model for humans. |
| Time scaling: Not applied. Cardiac sensitization is an exposure and blood concentration related threshold effect. Several studies have shown that blood concentrations of halocarbons do not increase greatly with time after 15 #x02013;55 min of exposure, and exposure duration did not influence the concentration at which the effect occurred. |
| Data adequacy: The study was well conducted and documented. Supporting data include both human and animal studies. Animal studies covered acute, subchronic, and chronic exposure durations and addressed systemic toxicity as well as neurotoxicity, reproductive and developmental effects, cardiac sensitization, genotoxicity, and carcinogenicity. Other effects in animal studies occurred at much higher concentrations or with repeated exposures; the latter are not relevant for setting short-term exposures. No deaths occurred in several species of animals exposed for various periods of time to concentrations less than those requiring supplemental oxygen (approximately 700,000 ppm). |
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